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Sweat news for diabetics

A brain enzyme known as prolyl endopeptidase (PREP) plays a key role in sensing and controlling glucose levels in the blood, a discovery that’s likely to herald new treatments for diabetes of both Type 1 and 2. Found in the ventromedial nucleus, PREP is part of the hypothalamus that kicks off the steps that control glucose in the blood, Lead author Sabrina Diano, a professor at Yale University School of Medicine, said.

The study went beyond the already known fact that ventromedial nucleus has brain cells capable of sensing glucose and revealed that the brain gains its ability to sense glucose because of PREP. On detecting rising glucose levels, they instruct the pancreas to secrete more insulin, which moderates glucose levels and prevents diabetes.

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