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Glioblastoma

Researchers find drug that could check spread of glioblastoma

A drug that targets a protein called TROY thereby limiting the spread of glioblastoma, the most common and aggressive brain tumour has been developed by researchers in Phoenix, US. Called propentofylline or PPF, the drug helps in increasing the potency of temozolomide (TMZ), and radiation, which are standard response to the deadly cancer. The researchers have claimed that PPF decreases the expression and curbs the invasion of glioblastoma cells and alongside increases their vulnerability to TMZ and radiation.

The senior author of the study Mr Nhan Tran at the Phoenix-based Translational Genomics Research Institute (Tgen), in Phoenix, US said that in combination with TMZ and radiation PPF could improve the clinical outcome for patients of brain tumour.

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