The blood-brain-barrier has for long blocked the delivery of effective cancer drugs directly to malignant tumour affected areas in the brain. This may, however, be about to change. In a breakthrough achievement with exciting implications for brain cancer treatment, doctors have succeeded in breaching this barrier.
Said Dr Todd Mainprize, the lead investigator at The Sunnybrook Health Sciences Centre, Hurvitz: “The blood-brain barrier (BBB) has been a stubbornly impeded efforts to deliver efficacious therapies to treat tumours. Now, we can temporarily breach this barrier and administer chemotherapy directly to the brain tumour.” This means that some of the most exciting and novel brain tumours therapeutics could now reach tumour cells lying beyond the blood brain barrier.