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Parkinson's Disease

Immune gene can check Parkinson’s disease

According to a research team at the University of Copenhagen, Denmark Parkinson’s disease (PD) and dementia can be thwarted by functional changes in an immune regulating gene. The team of researchers reported in a recent edition of Cell that functional changes in Interferon-beta (IFNbeta), an immune regulating gene are associated with non-inheritable PD. Their study revealed that it was possible to prevent neuronal death and the effects of PD with IFNbeta gene therapy. For neurons to recycle waste proteins they need IFNbeta, the researchers found. Its absence, in other words, leads to the accumulation of these junk proteins in structures called Lewy bodies which are implicated in Parkinson’s disease.

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